Synephrine, or, more specifically, p-synephrine, is analkaloid, occurring naturally in some plants and animals, as well as inapproved drugs products in form of its m-substituted analog known asneo-synephrine. p-synephrine (or formerly Sympatol and oxedrine [BAN]) andm-synephrine are known for their longer acting adrenergic effects compared tonorepinephrine. This substance is present at very low concentrations in commonfoodstuffs such as orange juice and other orange (Citrus species) products,both of the "sweet" and "bitter" variety. The preparationsused in Traditional Chinese Medicine (TCM), also known as Zhi Shi, are theimmature and dried whole oranges from Citrus aurantium (Fructus AurantiiImmaturus). Extracts of the same material or purified synephrine are alsomarketed in the US,sometimes in combination with caffeine, as a weight-loss-promoting dietarysupplement for oral consumption. While the traditional preparations have beenin use for millennia as a component of TCM-formulas, synephrine itself is notan approved OTC drug. As a pharmaceutical, m-synephrine is still used as asympathomimetic (i.e. for its hypertensive and vasoconstrictor properties),mostly as a parenteral drug in the treatment of emergencies such as shock andrarely p.o. for the treatment of bronchial problems associated with asthma andhay-fever.
In physical appearance,synephrine is a colorless, crystalline solid and is water-soluble. Itsmolecular structure is based on a phenethylamine skeleton, and is related tothose of many other drugs, and to the major neurotransmitters epinephrine andnorepinephrine.
Some dietary supplements, sold for the purposes ofpromoting weight-loss or providing energy, contain synephrine as one of severalconstituents. Usually, the synephrine is present as a natural component ofCitrus aurantium ("bitter orange"), bound up in the plant matrix, butcould also be of synthetic origin, or a purified phytochemical (i.e. extractedfrom a plant source and purified to chemical homogeneity).,The concentration rangefound by Santana and co-workers in five different supplements purchased in theUS was about 5 – 14 mg/g.
|Appearance||Light-Brown Fine powder|
|Synephrine||NLT 30.0% by HPLC|
|Loss on Drying||NMT 6.0%|
|Residue on ignition||NMT 8.0%|
|Particle size||80 Mesh 95% Passes|
|Total Plate Count||NMT 1000cfu/g|
1, What kinds of certificates can you offer?
Foodchem is an ISO2008 9001 certified company, as for Methyl-Sulfonyl-Methane(MSM), we can offer HAPPC, KOSHER, HALAL Certificates, ect.
2, Is Foodchem a manufacturer or just a trading company?
Foodchem is both manufacturer and trading company, we are Methyl-Sulfonyl-Methane(MSM) distributor, at the same time, we are manufacturer of other products.
3, What is the Min Order Quantity of Methyl-Sulfonyl-Methane(MSM)?
Different products have different MOQ, for Methyl-Sulfonyl-Methane(MSM), the MOQ is 500kg.
4, What is the price of Methyl-Sulfonyl-Methane(MSM)?
Foodchem is a famous supplier and manufacturer of Methyl-Sulfonyl-Methane(MSM) in China, and has been corporate with many Methyl-Sulfonyl-Methane(MSM) suppliers for several years, we can provide you with cost-effective Methyl-Sulfonyl-Methane(MSM).
5, How long shall we wait for your reply?
We can guarantee to reply your inquiries of Methyl-Sulfonyl-Methane(MSM) in less than 24 hours in working days.
6, What kinds of transportation types can you provide?
Our main transportation methods include air transportation, land transportation and water transportation.
7, What kinds of payment terms can you accept?
The most commonly used payment terms are T/T, L/C, D/P, D/A, etc.
8, How long will I receive my good?
Foodchem has its own EDC warehouse in Shanghai, when your purchase order has been confirmed, inventory products will deliver within 1 week, other products delivery in 2 weeks.